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Howard Levy

Howard Levy

Company: Catalyst Biosciences

Job title: Chief Medical Officer


A Tale of Two Subcutaneous Coagulation Factors 12:30 pm

High potency clotting factors are required for subcutaneous (SQ) delivery Pharmacokinetics (PK) of SQ delivery results in prolonged half-life and summation of blood levels SQ coagulation factors have very different PK: Cmax, Tmax, half-life, mean residence time, AUC and distribution across compartments Activity levels are more sustained with SQ injection than intravenous (IV) infusion Prophylaxis…Read more

day: Day One

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